Description
A total iron-binding capacity (TIBC) test measures the blood’s ability to attach itself to iron and transport it around the body. A transferrin test is similar. If you have iron deficiency (a lack of iron in your blood), your iron level will be low but your TIBC will be high.
What does iron and TIBC test for?
Total iron binding capacity (TIBC) is a blood test to see if you have too much or too little iron in your blood. Iron moves through the blood attached to a protein called transferrin. This test helps your health care provider know how well that protein can carry iron in your blood.
What does iron saturation mean in a blood test?
Summary. Iron saturation refers to the amount of iron that is present in the blood. Low iron saturation means that there is a low amount of iron in the blood. Transferrin binds to and transports iron, while ferritin stores this mineral in the body.
What does it mean if my TIBC is high?
High TIBC means that you have low levels of iron. When there isn’t much iron to attach to, you’ll have a lot of free transferrin in your blood. Low iron levels can lead to iron deficiency anemia, a condition in which your body doesn’t have enough iron to make healthy red blood cells.
Why would iron and iron saturation be high?
Key Points. Secondary iron overload results from excess absorption of iron, repeated blood transfusions, or excess oral intake. The effects of secondary iron overload include liver disease (leading to cirrhosis), skin pigmentation, diabetes, arthropathy, erectile dysfunction, and sometimes heart failure.
What are the 3 stages of iron deficiency?
The serum transferrin receptor level rises (> 8.5 mg/L). During stage 3, anemia with normal-appearing RBCs and indices develops. During stage 4, microcytosis and then hypochromia develop. During stage 5, iron deficiency affects tissues, resulting in symptoms and signs.
What are the symptoms of low iron saturation?
Symptoms
- Extreme fatigue.
- Weakness.
- Pale skin.
- Chest pain, fast heartbeat or shortness of breath.
- Headache, dizziness or lightheadedness.
- Cold hands and feet.
- Inflammation or soreness of your tongue.
- Brittle nails.
What is a normal iron saturation level for a woman?
Normal levels are generally between 35.5 and 44.9 percent for adult women and 38.3 to 48.6 percent for adult men. These values may change depending on your age.
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